Non-Invasive Ventilation
(NIV) and Aerogen
Glossary
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Aerogen Clinical Evaluation

Aerosol Drug Delivery with Aerogen During Non-Invasive Ventilation: Patients with COPD

(Galindo-Filho VC, Alcoforado L, Rattes C, et al. 2019)

Crossover study involving 9 stable patients with moderate-to-severe COPD randomly assigned to receive aerosol administration.

Group 1: NIV + Aerogen

Group 2: NIV + jet Nebulizer

Primary outcome was radioaerosol inhaled into the lungs

~4x more medication was delivered to the lungs using Aerogen during Non-Invasive Ventilation compared to a jet Nebulizer in patients with moderate-to-severe COPD.